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Issue Date: March 2007

Top Docs Cancer Tumors

A new drug discovered by Dr. Tatiana Byzona and her research team at Cleveland Clinic could become competition for drugs currently used  to block new blood-vessel growth for tumors that lead to cancers such as melanoma, breast, prostate and colorectal.

When blood vessels are blocked, the tumor’s food supply is cut off and it dies. Byzona’s team is testing a compound that has proven to stop an interaction between two receptors unique to these tumor-feeding blood vessels. This cuts off the pipeline that helps tumors develop while only targeting tumor tissues — something current drugs could not do.  

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